Two sample MR report
SPATA20_T Proliferating against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0221142 | 0.1582231 | 0.9016497 |
| Weighted median | 4 | 0.0221888 | 0.0108442 | 0.0407415 |
| Inverse variance weighted | 4 | 0.0219598 | 0.0094042 | 0.0195371 |
| Simple mode | 4 | 0.0228579 | 0.0145000 | 0.2130224 |
| Weighted mode | 4 | 0.0225036 | 0.0143771 | 0.2154942 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0700940 | 2 | 0.9655600 |
| Inverse variance weighted | 0.1479627 | 3 | 0.9855172 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0287385 | 0.1029872 | 0.8064147 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.02e-05 | 0 | TRUE | 0.5473638 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
